Bioanalytical

The Bioanalytical Laboratory of LAB Research (Canada) offers GLP and non-GLP compliant bioanalytical analysis for non-clinical studies performed in house and as well for studies conducted in Sponsor's facility. Analysis of plasma/serum or other biological matrices is performed to determine the concentration of the test item in selected biological matrices for pharmacokinetic / toxicokinetic analysis.  LAB Research performs method development for new compound or methodology transfer of an existing method. In each case, the method is fully validated according to GLP principles. With more than 50 years of cumulative staff experience, the new Bioanalytical service ensures that our clients receive professional and high quality support in the conduct of their studies.

Facilities
 Dedicated 800 sq. ft. laboratories with specific areas for:
 LC-MS instrument room
 HPLC instrument room
 Extraction and prep room
 Balance room
 Dedicated washing area

Equipment

 Two HPLC- MS/MS systems
 Shimadzu Prominence UFLC systems
 Applied Biosystems / MDS SCIEX API 4000 MSMS (Analyst 1.5)

Staff

 Scientists with more than 30 years of cumulative experience in bioanalytical method development/method validation using LC-MS/MS technology.

Activities

 Method Development
 Method Transfer
 Method Validation
 Sample analysis to support PK / TK studies and the inhalation toxicology studies